产品货号：
Z12501
中文名称：
CA15-3/MUC1抗体
英文名称：
Anti-CA15-3/MUC1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CA15-3/MUC1 Antibody |
| 指标别名 | CA15 3;CA153;CA15-3;Carcinoma associated mucin;CD227;EMA;Episialin;H23AG;KL-6;MAM6;MUC 1;MUC1;MUC1 beta;MUC1 CT;MUC1 NT;MUC1/CA15-3 C-terminal;Mucin 1;Peanut reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor associated mucin |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,IHC-F |
| 基因名称 | MUC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse MUC1 recombinant protein (Position:S474-L630).Mouse MUC1 shares 87% amino acid (aa) sequence identity with human MUC1. |
| 实际分子量 | 122KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mucin 1,cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans.This gene encodes a membrane-bound protein that is a member of the mucin family.Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces.It is mapped to 1q22.Mucin 1 is a transmembrane mucin normally expressed on the apical borders of secretory epithelial cells.Overexpression of Mucin 1 is often associated with colon,breast,ovarian,lung and pancreatic cancers.The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity.Mucin 1 stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells.This gene also can suppress pulmonary innate immunity,and its antiinflammatory activity may play an important modulatory role during microbial infection. |
| Uniprot ID | Q02496 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | mucin 1,cell surface associated |
| 蛋白名全称 | Mucin-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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